With the rapid rise in bioengineering, bio-technology, bio-scientific economics, research commercialism, and the unraveling of genetic mysteries, many clinical and laboratory situations arise that bring bio-ethical urgencies to the forefront. Based on the author's years of teaching and private and hospital practice, Bioethics' Rise, Decline, and Fall offers guiding conclusions to today's medical quandaries.

"Les Dilemmes de la métaphysique pure" de Charles Renouvier. Philosophe français (1815-1903).

This is a new release of the original 1939 edition.

This article focuses on the ways that sexual risk behaviors are related to race, class, and gender among low-income, culturally diverse women in South Florida. Data concerning sexual risk and gender are presented in terms of race and class variations. Results indicate that, in general, these women have a high degree of knowledge about acquired immune deficiency syndrome, a quite contemporary awareness of women's gendered subordination, and a lack of trust in heterosexual relationships. Attitudes, beliefs, and knowledge, however, are not (...) translated into sexual behaviors with men partners that would reduce their vulnerability to infection with the human immunodeficiency virus. The data indicate that race is a major factor that places women into an underclass position. Consequently, without socioeconomic resources, gendered behaviors have a direct influence on sexual risk. Multivariate analyses indicate that those women who are sex workers are significantly more likely to negotiate safe sex with clients than with main partners. The research not only challenges mainstream thinking about race, class, and gender but also provides overdue information on the vulnerability of women to HIV infection. (shrink)

The basic principles of scientific research from the great French physiologist whose contributions in the 19th century included the discovery of vasomotor nerves; nature of curare and other poisons in human body; more.

What makes us responsive, however occasionally, to moral demands? Why do people sometimes own up, go off to fight unwillingly in what they consider to be just wars, refrain from stealing a march on friends, and so on, even when they could by doing otherwise reap advantages far outweighing, in the scales of ordinary prudential rationality, any consequent disadvantage? Why has morality such a hold over us?

Among the miscellany of philosophical achievements bequeathed us by the Enlightenment is the account, worked out by Hobbes, Locke, Hume and others, of the conditions for the existence of the kind of civil or commercial association that depends upon contract. The theory of civil association has subsequently exercised the kind of fascination for moral philosophers that a highly successful theory is apt to exercise in any field of enquiry: it has, that is, both inspired later writers and to some extent (...) restricted their horizons. (shrink)

In lieu of an abstract, here is a brief excerpt of the content:Bernard Harrison THE TRUTH ABOUT METAPHOR GOTTLOB frece introduced into philosophy two doctrines whose subsequent influence, on analytic philosophers at least, has been momentous. One is the doctrine that to understand a sentence is to know how to set about establishing die trudi-value of an assertion couched in those words. The other is the doctrine that a word has meaning only in the context of a sentence. (...) These doctrines make it hard to understand metaphor. They create difficulties, especially, for any theory of metaphor which assumes the intelligibility of talk about two kinds of meaning, literal and metaphorical. Frege's doctrines allow only one kind of meaning: one connected essentially with the issue of truth and falsity. But it is only when we take them literally that metaphorical sentences acquire a truth value: usually false. Two obvious suggestions offer ways of getting around this. The first is the suggestion diat metaphors are condensed or disguised similes: true or (sometimes) false statements about similarity. The second is the suggestion that a term used in a metaphorical context just has a different literal meaning from the one it has in a sentence intended to be taken literally. Neither is very plausible. The first reduces a metaphorical comparison, "Man is a wolf," to a literal statement of similarity, "Men are like wolves." But what similarity, exactly, is the statement supposed to be asserting? Perhaps that men prey upon one anodier, as wolves are supposed to do. But dien "prey" can only be meant metaphorically, at which point die puzzle revives. As Goodman says of die attempt to find a simile in the metaphorical assertion diat a picture is sad, "What die simile says in effect is that person and picture are alike in being sad, die one literally and the odier metaphorically. Instead of metaphor reducing to simile, simile reduces to metaphor; or radier, the difference between simile and metaphor is negligible." ' 38 Bernard Harrison39 An equally fatal objection to the second suggestion is diat it is only ifwe take die terms which compose a metaphor in their plain everyday senses that they compose a metaphor. As R. M. J. Dammann puts it, "IfGod is a rock in a different sense from that in which Gibraltar is one, then both are really, literally, rocks, just as what one buys in a sweetshop is rock, though a dissatisfied customer might call it such metaphorically."2 It cannot, in odier words, be literally true diat die process of understanding a metaphor involves changing the sense ofits constituent expressions, odierwise metaphor would evaporate in die reader's grasp into literality. What this suggests is diat what makes a sentence metaphorical is not any change in the meaning of its constituent expressions, but the way in which those expressions, with dieir plain everyday meanings, are combined in the sentence. What we need, perhaps, ifwe are to begin to understand metaphor, is not a dieory ofmetaphorical meaning, but an account of what it is to assert metaphorically: an account, diat is, which would operate at the level of die sentence rather than at diat of die word. But this returns us to Frege's two doctrines. If the meaning of a word is to be wholly identified with die contribution it makes to die determination of a truth value for each sentence in which it occurs, dien it is difficult to see how the constituents of a sentence could determine anything odier than a plain, literal meaning for the sentence as a whole. What I shall try to show in this essay is that this difficulty can be overcome : that we can give a satisfactory account of the semantic mechanisms of metaphor without giving up either of Frege's doctrines. As Frege thought, understanding a sentence is knowing how to set about establishing the truth or falsity ofassertions couched in diose words. But to say what, exacdy, someone knows in knowing diat demands, I shall argue, a more complicated story than Fregeans have supposed. First, diough, I want to consider a more radical strategy dian mine for squaring Frege's doctrines with our experience of metaphor, proposed by Donald Davidson.3 Davidson holds widi Frege that the... (shrink)

Directional deep brain stimulation contacts provide greater spatial flexibility for therapy than traditional ring-shaped electrodes, but little is known about longitudinal changes of impedance and orientation. We measured monopolar and bipolar impedance of DBS contacts in 31 patients who underwent unilateral subthalamic nucleus deep brain stimulation as part of a randomized study. At different follow-up visits, patients were assigned new stimulation configurations and impedance was measured. Additionally, we measured the orientation of the directional lead during surgery, immediately after surgery, and (...) 1 year later. Here we contrast impedances in directional versus ring contacts with respect to local anatomy, active stimulation contact, and over time. Directional contacts display larger impedances than ring contacts. Impedances generally increase slightly over the first year of therapy, save for a transient decrease immediately post-surgery under general anesthesia during pulse generator placement. Local impedances decrease at active stimulation sites, and contacts in closest proximity to internal capsule display higher impedances than other anatomic sites. DBS leads rotate slightly in the immediate postoperative period but otherwise remain stable over the following year. These data provide useful information for setting clinical stimulation parameters over time. (shrink)

Conventional agency theory typically focuses on a unidirectional problem, in which an agent behaves opportunistically against the interests of a principal. Yet, this conceptualization is too limited to fully describe all aspects of principal–agent relationships. This article presents a more comprehensive framework explaining a potential three-directional problem—that is, agents behave opportunistically against the interests of principals, principals behave opportunistically against the interests of agents, and relationships between agents and principals representing confluence of interests affect the interests of third-party stakeholders. The (...) article provides evidence of these problems, describes their unique characteristics, and outlines implications for society. It concludes with a discussion focusing on the implications of the proposed framework for purported governance solutions, the ongoing debate between shareholder and stakeholder views of the firm, and business practices. (shrink)

This paper attempts to refute the familiar sceptical argument based upon the theoretical possibility of systematic transpositions of colours in different observers? colour?vision. The force of this argument lies in its apparent demonstration that cases of transposed colour?vision would be on a quite different cognitive footing from ordinary cases of colour?blindness; since colour transposition, unlike colour?blindness, could not possibly have any effect on the use of language by a person who suffered from it. It is argued (1) that this demonstration (...) works only if we assume the truth of a certain theory of the logical nature of our colour vocabulary, and (2) that this theory is false. (shrink)

Recent perspectives on community investments suggest that they are opportunities for firms to create value for shareholders and other stakeholders. However, many corporate managers are still influenced by a widely held belief that such investments erode profits and are therefore unjustifiable from an agency perspective. In this paper, we refine and test theory regarding countervailing forces that influence community-based firm performance. We hypothesize that high levels of available slack will be associated with higher community-based performance, but that this relationship will (...) be moderated by three important governance variables: board independence, investment fund ownership, and CEO ownership. We find support for our hypotheses in longitudinal study of a large sample of U.S. corporations. (shrink)

How can literature, which consists of nothing more than the description of imaginary events and situations, offer any insight into the workings of "human reality" or "the human condition"? Can mere words illuminate something that we call "reality"? Bernard Harrison answers these questions in this profoundly original work that seeks to re-enfranchise reality in the realms of art and discourse. In an ambitious account of the relationship between literature and cognition, he seeks to show how literary fiction, by (...) deploying words against a background of imagined circumstances, allows us to focus on the roots, in social practice, of the meanings by which we represent our world and ourselves. Engaging with philosophers and theorists as diverse as Wittgenstein, Sartre, Merleau-Ponty, Foucault, Derrida, F. R. Leavis, Cleanth Brooks, and Stanley Fish, and illustrating his ideas through readings of works by Swift, Woolf, Appelfeld, and Dickens, among others, this book presents a systematic defense of humanism in literary studies, and of the study of the Humanities more generally, by a distinguished scholar. (shrink)

Written by a non-Jewish analytic philosopher, this book addresses the issue of whether, and to what extent, current opposition to Israel on the liberal-left embodies anti-Semitic stances. It argues that the dominant climate of liberal opinion disseminates, however inadvertently, a range of anti-Semitic assertions and motifs of the most traditional kind. It advocates a return to an unrestricted anti-racism which would allow liberals to defend Palestinian interests without demonizing Jews.

Bernard Harrison; XIII—Meaning and Mental Images, Proceedings of the Aristotelian Society, Volume 63, Issue 1, 1 June 1963, Pages 237–250, https://doi.org/10.10.

Bernard Harrison; XIII—Meaning and Mental Images, Proceedings of the Aristotelian Society, Volume 63, Issue 1, 1 June 1963, Pages 237–250, https://doi.org/10.10.